| Product Name | Alarelin Acetate |
| Synonyms | Alarelin, LHRH-A, [D-Ala6, des-Gly10]-LHRH ethylamide, (Des-Gly10, D-Ala6, Pro-NHEt9)-LHRH, Surfagon |
| CAS Number | 79561-22-1 (acetate / diacetate salt) |
| Sequence (3-Letter) | pGlu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt |
| Sequence (1-Letter) | pGlu-HWSYaLR-Pro-NHEt (a = D-Ala; des-Gly10; Pro9 ethylamide) |
| Molecular Formula | C₅₆H₇₈N₁₆O₁₂ (free base) |
| Molecular Weight | 1167.31 (free base); acetate salt ≈ 1227.4 |
| Category | Drug Peptide – GnRH (LHRH) Agonist |
| Purity | ≥98% (by HPLC) |
| Appearance | White to off-white lyophilized powder |
| Counter Ion | Acetate (supplied as the acetate / diacetate; salt form per specification) |
| Peptide Content | ≥80% (per specification) |
| Solubility | Soluble in water |
| Storage | -20°C, desiccated, protected from light |
| Available Scale | mg – kg (research quantities to scale-up batches) |
| QC Documentation | COA, HPLC, MS identity (additional API/regulatory documentation on request) |
| Usage | For research and pharmaceutical development use, and as a reference standard or active pharmaceutical ingredient for manufacturing. Not for human or veterinary use; not for sale to patients. Any therapeutic use is subject to applicable regulatory approval. |
Alarelin Acetate is the acetate salt of alarelin, a synthetic nonapeptide and gonadotropin-releasing hormone (GnRH) agonist, also called an LHRH agonist (CAS 79561-22-1). Its sequence is pGlu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt: it is built from natural GnRH by adding a D-alanine at position six, removing the C-terminal glycine, and capping the proline as an ethylamide. We supply it as a white powder for research and pharmaceutical development.
Alarelin is a GnRH agonist, and a potent one. Its structural changes make it bind the GnRH receptor tightly and resist breakdown, so it is many times more active than natural GnRH. Given continuously it first stimulates the pituitary and then desensitises it, which lowers the release of LH and FSH and, in turn, the body's sex hormones; given in short pulses it can instead drive ovulation.
In research and clinical use, alarelin has been used to induce ovulation and in the management of endometriosis, and it is also used in animal reproduction. This is background information only; the material we supply is for research and pharmaceutical manufacturing use, and is not for human or veterinary use and not for sale to patients.
We supply Alarelin Acetate with a certificate of analysis, HPLC purity data, and mass-spec identity confirmation. Additional documentation for API and regulatory work is available on request, and acetate content and purity can be set to your specification.
Yes. We manufacture Alarelin Acetate in-house and supply from research quantities up to scale-up batches. Contact us with your required purity, salt form, and quantity for a quote.
Alarelin Acetate is the acetate salt of alarelin, a synthetic nonapeptide and gonadotropin-releasing hormone (GnRH) agonist, also known as an LHRH agonist and by the code LHRH-A. We supply it as a raw material for research and pharmaceutical development.
Alarelin is a nine-residue peptide with the sequence pGlu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt. It is derived from natural GnRH by three changes: a D-alanine replaces the glycine at position six, the C-terminal glycine is removed, and the proline is capped as an N-ethylamide. These changes make it a potent, long-acting agonist. Its CAS number is 79561-22-1, the free-base molecular formula is C56H78N16O12, the free-base molecular weight is about 1167, and the acetate salt is about 1227.
Alarelin is an agonist at the GnRH receptor and binds it tightly, which is why supplier data describe it as many times more active than natural GnRH. Like other GnRH agonists such as triptorelin, continuous exposure first stimulates the pituitary and then desensitises it, lowering the release of luteinising hormone (LH) and follicle-stimulating hormone (FSH) and the sex hormones they control; shorter, pulsed exposure can instead be used to drive ovulation.
In research and clinical settings, alarelin has been used to induce ovulation and in the management of endometriosis, and it is also used in animal reproduction and aquaculture. This information is provided as scientific and reference background only. The material supplied by SynPeptide is intended for research and pharmaceutical manufacturing, is not for human or veterinary use, and is not for sale to patients; any therapeutic use is subject to applicable regulatory approval.
We supply Alarelin Acetate with a certificate of analysis, HPLC purity data, and mass-spectrometry identity confirmation, with further documentation available to support active pharmaceutical ingredient and regulatory work. Purity, salt form, and acetate content can be set to your specification for use as a reference standard or in process development.
We manufacture Alarelin Acetate by solid-phase synthesis, including the pyroglutamate, the D-alanine residue, and the C-terminal proline ethylamide, and supply it from research quantities through to scale-up batches. For related capabilities, see drug peptides, custom peptide synthesis, and peptide modification. Material is supplied for research and pharmaceutical manufacturing use only.
