| Product Name | Vasopressin |
| Synonyms | Arginine vasopressin (AVP), Argipressin, Antidiuretic hormone (ADH), Vasostrict, Pitressin |
| CAS Number | 11000-17-2 (arginine vasopressin; also 113-79-1) |
| Sequence (3-Letter) | H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH₂ (cyclic Cys1–Cys6 disulfide) |
| Sequence (1-Letter) | CYFQNCPRG-NH₂ (disulfide Cys1–Cys6) |
| Molecular Formula | C₄₆H₆₅N₁₅O₁₂S₂ |
| Molecular Weight | 1084.23 |
| Category | Drug Peptide – Vasopressin (V1/V2 Receptor Agonist) |
| Purity | ≥98% (by HPLC) |
| Appearance | White to off-white powder |
| Counter Ion | Acetate (salt form per specification) |
| Peptide Content | ≥80% (per specification) |
| Solubility | Soluble in water |
| Storage | -20°C, desiccated, protected from light |
| Available Scale | mg – kg (research quantities to scale-up batches) |
| QC Documentation | COA, HPLC, MS identity, disulfide-connectivity confirmation (additional API/regulatory documentation on request) |
| Usage | For research and pharmaceutical development use, and as a reference standard or active pharmaceutical ingredient for manufacturing. Not for human or veterinary use; not for sale to patients. Any therapeutic use is subject to applicable regulatory approval. |
Vasopressin, also called arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a natural cyclic nonapeptide hormone (CAS 11000-17-2). Its sequence is CYFQNCPRG-NH2, a nine-residue ring closed by a disulfide bond between two cysteines, with a C-terminal amide. It is the parent of analogs such as desmopressin and terlipressin. We supply it as a white powder for research and pharmaceutical development.
Vasopressin acts through two main receptors. At V1 receptors on the muscle of blood vessels it makes the vessels constrict, which raises blood pressure. At V2 receptors in the kidney it makes the collecting ducts reabsorb more water, which concentrates the urine and conserves body water. The disulfide ring is needed for both actions.
Clinically, vasopressin is used to raise blood pressure in some forms of shock, to treat central diabetes insipidus, and in other settings such as cardiac arrest and certain types of bleeding. This is background information only; the material we supply is for research and pharmaceutical manufacturing use, and is not for human or veterinary use and not for sale to patients.
We supply Vasopressin with a certificate of analysis, HPLC purity data, and mass-spec identity confirmation, and we can confirm the disulfide connectivity. Additional documentation for API and regulatory work is available on request, and salt form and purity can be set to your specification.
Yes. We manufacture Vasopressin in-house and supply from research quantities up to scale-up batches. Contact us with your required purity, salt form, and quantity for a quote.
Vasopressin, also known as arginine vasopressin (AVP) and antidiuretic hormone (ADH), is a natural cyclic nonapeptide hormone that controls water balance and blood pressure. It is known as a medicine under brand names such as Vasostrict and Pitressin. We supply it as a raw material for research and pharmaceutical development.
Vasopressin is a nine-residue peptide with the sequence H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2, closed into a ring by a disulfide bond between Cys1 and Cys6 and ending in a C-terminal amide. It is closely related to oxytocin, differing only at two positions, and it is the parent structure of the analogs desmopressin and terlipressin. Its CAS number is 11000-17-2 (also listed as 113-79-1), its molecular formula is C46H65N15O12S2, and its molecular weight is about 1084.
Vasopressin acts through G-protein-coupled receptors. At V1 receptors on vascular smooth muscle it triggers calcium release and constricts blood vessels, raising blood pressure. At V2 receptors in the kidney it works through cyclic AMP to insert water channels in the collecting ducts, so more water is reabsorbed and the urine is concentrated. The intact disulfide ring is required for binding at these receptors.
Vasopressin is used clinically to raise blood pressure in vasodilatory and septic shock, to treat central diabetes insipidus, and in settings such as cardiac arrest and some forms of bleeding. This information is provided as scientific and reference background only. The material supplied by SynPeptide is intended for research and pharmaceutical manufacturing, is not for human or veterinary use, and is not for sale to patients; any therapeutic use is subject to applicable regulatory approval.
Vasopressin is the parent of a family of clinically used analogs. Desmopressin is a longer-acting, V2-selective analog used mainly for its antidiuretic effect, while terlipressin is a long-acting prodrug used for its vasoconstricting action. All three share the disulfide-bonded ring.
We manufacture Vasopressin by solid-phase synthesis with controlled disulfide formation, and supply it from research quantities through to scale-up batches. For related capabilities, see drug peptides and custom peptide synthesis. Material is supplied for research and pharmaceutical manufacturing use only.
